Apentix/AP Biology/Unit 2: Cell Structure and Function/Question
AP Biologyeasymcq1 pt

After weeks of barbiturate exposure, a patient's liver cells contain noticeably more smooth endoplasmic reticulum than before. Why does this change occur?

A.More smooth ER membrane raises production of the enzymes that chemically modify fat-soluble drugs
B.Extra ribosomes on smooth ER speed translation of the drug for destruction
C.Smooth ER wraps barbiturates in vesicles that dump them outside the body
D.The added membrane converts barbiturates directly into ATP

Explanation

Core Concept

Smooth ER membranes house cytochrome-associated enzymes that hydroxylate and otherwise modify lipid-soluble toxins, including barbiturates. Repeated exposure induces growth of this membrane system, enlarging the cell's detoxification capacity. Because the modifying enzymes are membrane residents, extra sheet area supports more catalytic throughput.

Correct Answer

AMore smooth ER membrane raises production of the enzymes that chemically modify fat-soluble drugs

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