Apentix/AP Biology/Unit 6: Gene Expression and Regulation/Question

AP Biologymediummcq1 pt

Which change is best described as epigenetic rather than a DNA-sequence mutation?

A.A deletion of three nucleotides from a coding region

B.A DNA-methylation change altering transcription without changing base sequence

C.A substitution of one DNA base pair for another

D.An insertion that shifts the gene's reading frame

Explanation

Core Concept

Epigenetic regulation changes gene expression or chromatin state without altering the underlying nucleotide sequence. Some epigenetic states are reversible and some are relatively stable, so reversibility is not the defining criterion.

Correct Answer

BA DNA-methylation change altering transcription without changing base sequence

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