Apentix/AP Biology/Unit 4: Cell Communication and Cell Cycle/Question
AP Biologymediummcq1 pt

Why do malignant tumors often require the accumulation of multiple driver mutations?

A.One mutation is always sufficient to create a malignant tumor
B.Mutations cannot affect pathways controlling cell growth or survival
C.Cancer develops without genetic or epigenetic alterations to cell regulation
D.Multiple control pathways for growth, survival, and genome stability often must be disrupted

Explanation

Core Concept

Cells use multiple safeguards to control proliferation, survival, genome integrity, and programmed cell death. Tumor progression commonly requires several driver alterations affecting different regulatory systems, which helps explain why cancer incidence generally increases with age.

Correct Answer

DMultiple control pathways for growth, survival, and genome stability often must be disrupted

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