Apentix/AP Biology/Unit 2: Cell Structure and Function/Question
AP Biologymediummcq1 pt

Acid hydrolases synthesized for lysosomes could wreak havoc if secreted accidentally. What tagging system steers them into lysosomes instead?

A.Mannose sugars on the enzymes get phosphorylated, and trans-Golgi receptors pack tagged enzymes into lysosome-bound vesicles
B.Their original signal peptides survive and dock on lysosomal surfaces
C.Random drift eventually lands every hydrolase inside a lysosome
D.Nuclear import tags divert the enzymes inward before lysosomes collect them

Explanation

Core Concept

Within the Golgi, a phosphotransferase installs phosphate markers on mannose residues of the hydrolases. By the trans-Golgi network, mannose-6-phosphate receptors catch the tagged enzymes and concentrate them into vesicles destined for lysosomes. Cells lacking this tag secrete the enzymes by default, the basis of I-cell disease.

Correct Answer

AMannose sugars on the enzymes get phosphorylated, and trans-Golgi receptors pack tagged enzymes into lysosome-bound vesicles

More Unit 2: Cell Structure and Function practice questions

Try a random question →

Practice more AP Biology questions with full explanations

Practice Unit 2: Cell Structure and Function Questions →