AP Biologyeasymcq1 pt

Which option pairs each stage of aerobic glucose breakdown with its correct cellular location?

A.Glycolysis in the cytosol, pyruvate oxidation and the citric acid cycle in the mitochondrial matrix, oxidative phosphorylation across the inner mitochondrial membrane
B.Glycolysis in the matrix, the citric acid cycle in the cytosol, oxidative phosphorylation on the outer membrane
C.All stages share the matrix so intermediates never diffuse between compartments
D.Glycolysis on the inner membrane, the citric acid cycle in the cytosol, oxidative phosphorylation dissolved in the matrix fluid

Explanation

Core Concept

Glycolysis occurs in the cytosol. Pyruvate oxidation and most citric-acid-cycle reactions occur in the mitochondrial matrix, whereas the respiratory electron-transport chain and ATP synthase are located in the inner mitochondrial membrane. Succinate dehydrogenase is an important exception because it is an inner-membrane enzyme that also participates in the citric acid cycle.

Correct Answer

AGlycolysis in the cytosol, pyruvate oxidation and the citric acid cycle in the mitochondrial matrix, oxidative phosphorylation across the inner mitochondrial membrane

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