Apentix/AP Biology/Unit 3: Cellular Energetics/Question
AP Biologyeasymcq1 pt

Many enzymes flex slightly around their substrates during binding, a behavior called induced fit. How does this movement aid catalysis?

A.It closes reactive groups tightly around the substrate, straining specific bonds and aligning them for the transition state
B.It widens the active site permanently so nearly any cellular molecule can enter and react
C.It heats the substrate by friction until spontaneous ignition drives the reaction forward
D.It snaps shut behind departing products, ejecting them faster from the finished enzyme

Explanation

Core Concept

Induced fit means substrate binding can change the enzyme's conformation so catalytic groups are positioned more effectively and the transition state is stabilized. Depending on the enzyme, conformational changes may also orient substrates, strain particular bonds, or alter solvent exposure. Excluding water is one possible mechanism in some active sites, not a universal feature of induced fit.

Correct Answer

AIt closes reactive groups tightly around the substrate, straining specific bonds and aligning them for the transition state

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